Tim Erichlandwehr

Doctoral Project

On-chip detection of biomolecules via exploitation of motor protein driven filaments

This phD project aims to exploit active transport of filaments via motor proteins (such as kinesin or myosin) for on-chip detection of biological analytes.  This way, passive transport phenomena can be complemented by active, motorprotein driven transport against concentration or charge gradients, which leads to an overall increase in control over processes at the nanoscale. The project aims to detect very small analyte amounts down to a single molecule. This is very promising for e.g. early detection of cancers via biomarkers or examine different ecological systems for trace amounts of environmental toxins. The successful execution of ths project, within the framework of the HELIOS program, will be supported by strong collaboration between Lund University and DESY,  as well as partners of the EU-funded research project 'bio4comp'.